CUBRe

PUBLICATIONS

2025

Adam, Y., Lujumb, I., Isewon, I.,…, Oyelade, J., …, & Ezekiel, A. (2025). A practical guide to identifying associations between tandem repeats and complex human traits using consensus genotypes from multiple tools. Nature Protocols (Accepted). Impact Factor: 13.1

 

Emmanuel, J., Isewon, I., & Oyelade, J. (2025). An optimized deep-forest algorithm using a modified differential evolution optimization algorithm: A case of host-pathogen protein-protein interaction prediction. Computational and Structural Biotechnology Journal. Impact Factor: 4.5 [Article]

 

Emmanuel, J., Isewon, I., Olasehinde, G., & Oyelade, J. (2025). An Extended Feature Representation Technique for Predicting Sequenced-based Host-pathogen Protein-protein Interaction. Current Bioinformatics. Impact Factor: 2.4 [Article]

 

Isewon, I., Alagbe, E., & Oyelade, J. (2025). Optimizing machine learning performance for medical imaging analyses in low-resource environments: The prospects of CNN-based Feature Extractors. F1000Research. Impact Factor: 3.2 [Article]


Emmanuel, J., Isewon, I., & Oyelade, J. (2025). Deep Forest Frameworks for Protein-Protein Interaction Prediction: A Review and Performance Evaluation. 7th International Conference on Signal Processing and Information Communication, ICSPIC 2024. Signals and Communication Technology. Springer, Cham. (Accepted). Impact Factor: 1.0

 

Adedeji EO, Ogunlana OO, Oduselu GO, Koenig R, Adebiyi E, Soremekun O, Fatumo S. (2025) Molecular docking and molecular dynamics simulation studies of inhibitor candidates against Anopheles gambiae 3-hydroxykynurenine transaminase and implications on vector control. Heliyon. Impact Factor: 3.4 [Article]

 

2024

Isewon, I., Binaansim, S., Adegoke, F., Emmanuel, J., & Oyelade, J. (2024). Machine learning methods for predicting essential metabolic genes from Plasmodium falciparum genome-scale metabolic network. PLOS ONE. Impact Factor: 2.9. [Article]

 

Akinwale, M., Emmanuel, J., Isewon, I., & Oyelade, J. (2024). Application of Deep learning Algorithms On Protein Function Prediction: A Systematic Review. International Conference on Science, Engineering and Business for Driving Sustainable Development Goals, SEB4SDG 2024.  Impact Factor: 3.4. [Article]

 

Emmanuel, J., Isewon, I., Olasehinde, G., & Oyelade, J. (2024). Current Trend and Performance Evaluation of Machine Learning Methods for Predicting Host-Pathogen Protein-Protein Interactions. International Conference on Science, Engineering and Business for Driving Sustainable Development Goals, SEB4SDG 2024. Impact Factor: 3.4. [Article]

 

Abimbola F Onyia, Toluwani A Nana, Elijah A Adewale, Ayomide O Adebesin, Bose E  Adegboye, Oluwatomiwa K Paimo, Opeyemi C De Campos, Titilayo I Bisi-Adeniyi, Oluwakemi A Rotimi, Jelili O Oyelade, Solomon O Rotimi, “Breast Cancer Phenotypes in Africa: A Scoping Review and Meta-Analysis”, (2023) JCO Global Oncology. Impact Factor: 4.5 [Article]

 

Adebayo, G. P., Oduselu, G. O., Aderohunmu, D. V., Klika, K. D., Olasehinde, G. I., Ajani, O. O., & Adebiyi, E. (2024). Structure-based design, and development of amidinyl, amidoximyl and hydroxamic acid based organic molecules as novel antimalarial drug candidates. Arabian Journal of Chemistry. Impact Factor: 5.3 [Article]

 

Oduselu, G. O., Elebiju, O. F., Ogunnupebi, T. A., Akash, S., Ajani, O. O., & Adebiyi, E. (2024). Employing Hexahydroquinolines as PfCDPK4 Inhibitors to Combat Malaria Transmission: An Advanced Computational Approach. Advances and Applications in Bioinformatics and Chemistry. Impact Factor: 6.5 [Article]

 

2023

Ziaei Jam, H., Li, Y., DeVito, R., Mousavi, N., Ma, N., Lujumba, I., Adam, Y., Maksimov, M., Huang, B., Dolzhenko, E., Qiu, Y., Kakembo, F. E., Joseph, H., Onyido, B., Adeyemi, J., Bakhtiari, M., Park, J., Javadzadeh, S., Jjingo, D., … Gymrek, M. (2023). A deep population reference panel of tandem repeat variation. Nature Communications. Impact Factor: 50.5 [Article]

 

OF Elebiju, OO Ajani, GO Oduselu, TA Ogunnupebi, E Adebiyi (2023). Recent advances in functionalized quinoline scaffolds and hybrids-Exceptional pharmacophore in therapeutic medicine. Frontiers in Chemistry. Impact Factor:  5.5 [Article]

 

Oduselu, G. O., Aderohunmu, D. V., Ajani, O. O., Elebiju, O. F., Ogunnupebi, T. A., & Adebiyi, E. (2023). Synthesis, in silico and in vitro antimicrobial efficacy of substituted arylidene-based quinazolin-4(3H)-one motifs. Frontiers in Chemistry. Impact Factor: 5.5 [Article]

 

Ogunnupebi, T. A., Ajani, O. O., Oduselu, G. O., Elebiju, O. F., & Adebiyi, E. (2023). Chemistry and Pharmacological diversity of Benzothiazepine—Excellent pathway to drug discovery. Journal of Molecular Structure. Impact Factor: 4.0 [Article]

 

Falola, O., Adam, Y., Ajayi, O., Kumuthini, J., Adewale, S., Mosaku, A., Samtal, C., Adebayo, G., Emmanuel, J., Tchamga, M. S. S., Erondu, U., Nehemiah, A., Rasaq, S., Ajayi, M., Akanle, B., Oladipo, O., Isewon, I., Adebiyi, M., Oyelade, J., & Adebiyi, E. (2023). SysBiolPGWAS: Simplifying post-GWAS analysis through the use of computational technologies and integration of diverse omics datasets. Bioinformatics. Impact Factor: 4.4 [Article]

 

Oladejo, D. O., Duselu, G. O., Dokunmu, T. M., Isewon, I., Oyelade, J., Okafor, E., Iweala, E. E., & Adebiyi, E. (2023). In silico Structure Prediction, Molecular Docking, and Dynamic Simulation of Plasmodium falciparum AP2-I Transcription Factor. Bioinformatics and Biology Insights. Impact Factor: 2.3 [Article]

 

2022

Adedeji, E. O., Oduselu, G. O., Ogunlana, O. O., Fatumo, S., Koenig, R., & Adebiyi, E. (2022). Anopheles gambiae Trehalase Inhibitors for Malaria Vector Control: A Molecular Docking and Molecular Dynamics Study. Insects. Impact Factor: 3.1 [Article]

 

Adegbite, G., Edeki, S., Isewon, I., Dokunmu, T., Rotimi, S., Oyelade, J., & Adebiyi, E. (2022). Investigating the epidemiological factors responsible for malaria transmission dynamics. IOP Conference Series: Earth and Environmental Science, 993(1), 012008. [Article]

 

Adam, Y., Sadeeq, S., Kumuthini, J., Ajayi, O., Wells, G., Solomon, R., Ogunlana, O., Adetiba, E., Iweala, E., Brors, B., & Adebiyi, E. (2022). Polygenic Risk Score in African populations: Progress and challenges. F1000Research. Impact Factor: 3.23. [Article]

 

Isewon, I., Soremekun, C., Adebiyi, M., Adetunji, C., Ogunleye, A. J., Bajeh, A. O., Asani, E. O., Gbadamosi, B., Soremekun, O., Udosen, B., Kintu, C., Ogundokun, R., Arowolo, M. O., Matiluko, O., Nashiru, O., Adebiyi, E., Ekenna, C., & Fatumo, S. (2022). Strengthening Bioinformatics and Genomics Analyses Skills in Africa for Attainment of the Sustainable Development Goals: Report of the 2nd Conference of the Nigerian Bioinformatics and Genomics Network. The American Journal of Tropical Medicine and Hygiene. [Article]

 

Afolabi, R., Chinedu, S., Ajamma, Y., Adam, Y., Koenig, R., & Adebiyi, E. (2022). Computational identification of Plasmodium falciparum RNA pseudouridylate synthase as a viable drug target, its physicochemical properties, 3D structure prediction and prediction of potential inhibitors. Infection, Genetics and Evolution: Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. Impact Factor: 2.6. [Article

 

Oduselu, G. O., Afolabi, R., Ademuwagun, I., Vaughan, A., & Adebiyi, E. (2022). Structure-based pharmacophore modeling, virtual screening, and molecular dynamics simulation studies for identification of Plasmodium falciparum 5-aminolevulinate synthase inhibitors. Frontiers in Medicine. [Article]

 

2021

Ghazal, H., Adam, Y., Idrissi Azami, A., Sehli, S., Nyarko, H. N., Chaouni, B., Olasehinde, G., Isewon, I., Adebiyi, M., Ajani, O., Matovu, E., Obembe, O., Ajamma, Y., Kuzamunu, G., Pandam Salifu, S., Kayondo, J., Benkahla, A., & Adebiyi, E. (2021). Plant genomics in Africa: Present and prospects. The Plant Journal: For Cell and Molecular Biology. Impact Factor: 6.2. [Article]

 

Ademuwagun, I. A., Rotimi, S. O., Syrbe, S., Ajamma, Y. U., & Adebiyi, E. (2021). Voltage-Gated Sodium Channel Genes in Epilepsy: Mutations, Functional Studies, and Treatment Dimensions. Frontiers in Neurology. Impact Factor: 3.4. [Article]

 

Beder, T., Aromolaran, O., Dönitz, J., Tapanelli, S., Adedeji, E. O., Adebiyi, E., Bucher, G., & Koenig, R. (2021). Identifying essential genes across eukaryotes by machine learning. NAR Genomics and Bioinformatics. [Article]

 

Oduselu GO, Ajani OO, Adebiyi E (2021).  Molecular docking studies of Amidoxime-containing heterocyclic compounds from Zinc database against homology modelled PfADSL. 5th International Conference on Science and Sustainable Development (ICSSD 2021). Impact Factor: 2.8. [Article]

Adam, Y., Samtal, C., Brandenburg, J.-T., Falola, O., & Adebiyi, E. (2021). Performing post-genome-wide association study analysis: Overview, challenges and recommendations. F1000Research. [Article]

Aromolaran O., Aromolaran D., Isewon I., Oyelade J (2021). “Machine learning approach to gene essentiality prediction: a review”. Briefings in Bioinformatics. Impact Factor: 13.9. [Article]

Aromolaran, O., Beder, T., Adedeji, E., Ajamma, Y., Oyelade, J., Adebiyi, E., & Koenig, R. (2021). Predicting host dependency factors of pathogens in Drosophila melanogaster using machine learning. Computational and Structural Biotechnology Journal. [Article]

 

Oduselu GO, Ajani OO, Ajamma YU, Adebiyi E (2021).  Structure-Based Drug Design in Discovering Target Specific Drugs against Plasmodium falciparum Adenylosuccinate Lyase. Tropical Journal of Natural Product Research. [Article]

 

2020

Aromolaran, O., Beder, T., Oswald, M., Oyelade, J., Adebiyi, E., & Koenig, R. (2020). Essential gene prediction in Drosophila melanogaster using machine learning approaches based on sequence and functional features. Computational and Structural Biotechnology Journal. [Article]

 

Fatumo, S., Ebenezer, T. E., Ekenna, C., Isewon, I., Ahmad, U., Adetunji, C., Oladipo, E. K., Adebiyi, M., Adebiyi, E., Nashiru, O., & Nigerian Bioinformatics and Genomics Network. (2020). The Nigerian Bioinformatics and Genomics Network (NBGN): A collaborative platform to advance bioinformatics and genomics in Nigeria. Global Health, Epidemiology and Genomics. [Article]

 

Adedeji, E. O., Ogunlana, O. O., Fatumo, S., Beder, T., Ajamma, Y., Koenig, R., & Adebiyi, E. (2020). Anopheles metabolic proteins in malaria transmission, prevention and control: A review. Parasites & Vectors. [Article]

 

2019

Oyelade, J., Isewon, I., Aromolaran, O., Uwoghiren, E., Dokunmu, T., Rotimi, S., Aworunse, O., Obembe, O., & Adebiyi, E. (2019). Computational Identification of Metabolic Pathways of Plasmodium falciparum using the k-Shortest Path Algorithm. International Journal of Genomics. Impact Factor: 2.6. [Article]

 

Rotimi S.O, Rotimi O.A, Salako A.A, Jibrin P., Oyelade J. and Iweala E.J(2019) “Gene Expression Profiling Analysis Reveals Putative Phytochemotherapeutic Target for Castration-Resistant Prostate Cancer”, Frontiers in Oncology. Impact Factor: 4.4.  [Article]

 

Olasehinde, G. I., Diji-geske, R. I., Fadina, I., Arogundade D., Darby, P., Adeleke A., Dokunmu T.M. Adebayo H. A. and Oyelade J,(2019) “Epidemiology of Plasmodium falciparum Infection and Drug Resistance Markers in Ota Area, Southwestern, Nigeria”, Infection and Drug Resistance. Impact Factor: 3. [Article]

 

Franklyn Nonso Iheagwam, Olubanke Olujoke Ogunlana, Oluseyi Ebenezer Ogunlana, Itunuoluwa Isewon and Jelili Oyelade (2019). “Potential anti-cancer flavonoids isolated from Caesalpinia bonduc young twigs and leaves: Molecular docking and in silico studies”. Bioinformatics and Biology Insights. [Article]

 

Oduselu, G. O., Ajani, O. O., Ajamma, Y. U., Brors, B., & Adebiyi, E. (2019). Homology Modelling and Molecular Docking Studies of Selected Substituted Benzo[d]imidazol-1-yl)methyl)benzimidamide Scaffolds on Plasmodium falciparum Adenylosuccinate Lyase Receptor. Bioinformatics and Biology Insights. Impact Factor: 3.7. [Article]

 

Aderohunmu D.V, Ajani OO, Oduselu GO, Adebiyi E (2019). Microwave-assisted synthesis of coumarin-based 5,6-dihydro pyrimidin-2(1H)-one derivatives. 3rd International Conference on Science and Sustainable Development (ICSSD 2019). [Article]

 

2018

Aworunse O.S, Adeniji O., Oyesola O.L., Isewon I., Oyelade J., Obembe O.O (2018). “Genomics Intervention in Medicine”.  Bioinformatics and Biology Insights. [Article]

 

Jelili Oyelade, Itunuoluwa Isewon, Efosa Uwoghiren, Femi Aromolaran (2018). In-silico knockout screening of plasmodium falciparum reactions and prediction of Novel essential reactions by analysing the metabolic network.  BioMed Research International. Impact Factor: 2.4. [Article]

 

Jelili Oyelade, Itunuoluwa Isewon, Damilare Olaniyan, Rotimi S. O, Jumoke Soyemi(2018): Effectiveness of model-based clustering in analyzing plasmodium falciparum RNA-seq time-course data. F1000 Research Journal. (ISI Index, Scopus) 

 

Soyemi, J., Isewon, I., Oyelade, J., & Adebiyi, E. (2018). Inter-Species/Host-Parasite Protein Interaction Predictions Reviewed. Current Bioinformatics. Impact Factor: 2.4. [Article]

 

2017

Ajani, O. O., Tolu-Bolaji, O. O., Olorunshola, S. J., Zhao, Y., & Aderohunmu, D. V. (2017). Structure-based design of functionalized 2-substituted and 1,2-disubstituted benzimidazole derivatives and their in vitro antibacterial efficacy. Journal of Advanced Research. Impact Factor: 11.4 [Article]

 

Jongeneel, C. V., Achinike-Oduaran, O., Adebiyi, E., Adebiyi, M., Adeyemi, S., Akanle, B., Aron, S., Ashano, E., Bendou, H., Botha, G., Chimusa, E., Choudhury, A., Donthu, R., & Isewon, I. (2017). Assessing computational genomics skills: Our experience in the H3ABioNet African bioinformatics network. PLOS Computational Biology. Impact Factor: 2.9. [Article]

 

Falola, O., Osamor, V. C., Adebiyi, M., & Adebiyi, E. (2017). Analyzing a single nucleotide polymorphism in schizophrenia: A meta-analysis approach. Neuropsychiatric Disease and Treatment. Impact Factor: 2.5. [Article]

 

Nicola J. Mulder, Ezekiel Adebiyi, Marion Adebiyi, Seun Adeyemi, Azza Ahmed, Rehab  Ahmed, Bola Akanle, Mohamed Alibi, Don L. Armstrong, Shaun Aron, Efejiro Ashano, Shakuntala Baichoo, Alia Benkahla, David K. Brown, Emile R. Chimusa, Faisal M. Fadlelmola, Dare Falola, Segun Fatumo, Kais Ghedira, Amel Ghouila, Scott Hazelhurst, Itunu Isewon, Segun Jung, Samar Kamal Kassim, Jonathan K. Kayondo, Mamana Mbiyavanga, Ayton Meintjes, Somia Mohammed, Abayomi Mosaku, Ahmed Moussa, Mustafa Muhammd, Zahra MunglooDilmohamud, Oyekanmi Nashiru, Trust Odia, Adaobi Okafor, Olaleye Oladipo, Victor Osamor, Jellili Oyelade, Khalid Sadki, Samson Pandam Salifu, Jumoke Soyemi, Sumir Panji, Fouzia Radouani, Oussama Souiai, Özlem Tastan Bishop (2017): “Development of Bioinformatics Infrastructure for Genomics Research in H3Africa”. Global Heart Journal – Elsevier.  Impact Factor: 0.713. [Article]

 

2016

Ashano, E., Isewon, I., Oyelade, J., & Adebiyi, E. (2016). Cluster analysis of Plasmodium RNA-seq time-course data identifies stage-specific co-regulated biological processes and regulatory elements. F1000Research. Impact Factor: 8.5. [Article

 

Mulder NJ, Adebiyi E, Alami R, Benkahla A, Brandful J, Doumbia S, Everett D, Fadlelmola FM, Gaboun F, Gaseitsiwe S, Ghazal H, Hazelhurst S, Hide W, Ibrahimi A, Jaufeerally Fakim Y, Jongeneel CV, Joubert F, Kassim S, Kayondo J, Kumuthini J, Lyantagaye S, Makani J, Mansour Alzohairy A, Masiga D, Moussa A, Nash O, Ouwe Missi Oukem-Boyer O, Owusu-Dabo E, Panji S, Patterton H, Radouani F, Sadki K, Seghrouchni F, Tastan Bishop Ö, Tiffin N, Ulenga N; H3ABioNet Consortium, Adebiyi M, Ahmed AE, Ahmed RI, Alearts M, Alibi M, Aron S, Baichoo S, Bendou H, Botha G, Brown D, Chimusa E, Christoffels A, Cornick J, Entfellner JB, Fields C, Fischer A, Gamieldien J, Ghedira K, Ghouila A, Ho Sui S, Isewon I, Isokpehi R, Dashti MJ, Kamng’ona A, Khetani RS, Kiran A, Kulohoma B, Kumwenda B, Lapine D, Mainzer LS, Maslamoney S, Mbiyavanga M, Meintjes A, Mlyango FE, Mmbando B, Mohammed SA, Mpangase P, Msefula C, Mtatiro SN, Mugutso D, Mungloo- Dilmohammud Z, Musicha P, Nembaware V, Osamor VC, Oyelade J, Rendon G, Salazar  GA, Salifu SP, Sangeda R, Souiai O, Van Heusden P, Wele M. ( 2016): H3ABioNet, a Sustainable Pan-African Bioinformatics Network for Human Heredity and  Health in Africa. Genome Research. Impact Factor: 14.63. [Article]

 

Jelili Oyelade, Itunuoluwa Isewon, Ifeoluwa Okunoren and Solomon Rotimi.(2016): “Modeling of the Glycolysis Pathway in Plasmodium falciparum using Petri Nets”. Bioinformatics and Biology Insights. [Article]

 

2015

Itunuoluwa Isewon,  Jelili Oyelade,  Benedikt Brors, Ezekiel Adebiyi (2015). In-silico Gene Regulatory Network of the Maurer’s Cleft Pathway in Plasmodium falciparum. Evolutionary Bioinformatics. Impact Factor: 2.03. [Article]

 

2014

H3Africa Consortium, Rotimi, C., Abayomi, A., Abimiku, A., Adabayeri, V. M., Adebamowo, C., Adebiyi, E., Ademola, A. D., Adeyemo, A., Adu, D., Afolabi, D., Agongo, G., Ajayi, S., Akarolo-Anthony, S., Akinyemi, R., Akpalu, A., Alberts, M., Alonso  Betancourt, O., Alzohairy, A. M., … Zar, H. (2014). Research capacity. Enabling the genomic revolution in Africa. Science. Impact Factor: 44.7. [Article]

 

2012

Victor Osamor, Ezekiel Adebiyi , Jelilli Oyelade and Seydou Doumbia (2012) “Reducing the time requirement of k-means Algorithm”, PloS One  Journal. Impact Factor: 3.7. [Article]

 

2011

Jelili Oyelade, Ezekiel Adebiyi, Itunu Ewejobi, Benedikt Brors and Roland Eils (2011) “Computational Identification of Signalling Pathways in Plasmodium falciparum”. Infection, genetics and evolution. Journal of molecular epidemiology and evolutionary genetics in infectious diseases – Elsevier,. Impact Factor: 3.264. [Article]